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Prof. Chester Lee Drum

Principal Investigator

Chester Drum, M.D. Ph.D., is an assistant professor at the National University of Singapore, a consultant cardiologist at the National University Hospital and director of the clinical trial innovation lab at TLGM, A*STAR. He is a Singapore permanent resident and currently maintains both internal medicine and cardiology board certifications in the US and Singapore. Dr. Drum received an M.D. and Ph.D. from the University of Chicago. He was trained in medicine at the University of California, San Diego and as a cardiologist at Brigham and Women’s Hospital (Harvard Medical School), in Boston. He then moved to Massachusetts Institute of Technology (MIT) where he was director of translational medicine for the regulatory innovation group, MIT-NEWDIGS. While at MIT, he received the Burroughs Wellcome Career Award for Medical Scientists. In Singapore, he has been a recipient of a Clinician Scientist Award from the NMRC.

Dr. Drum’s current research centers on mass spectroscopy for precision medicine and clinical trial design. Specifically, the lab focuses on new forms of novel biomarker detection and multi-omics analyses of large patient cohorts. As a practicing consultant, Dr. Drum oversees trial design, patient recruitment, pre-analytical protocol development and both quantitative and high-resolution mass spectroscopy technique development and validation. A central thrust of the research program is to define critical unmet in established clinical workflows uniquely suited for LCMS technology. Dr. Drum currently oversees 7 active IRB protocols, three SMART innovation awards and is currently the primary investigator on a multimillion dollar, multi-institutional, 3,000 person clinical trial in Singapore. He has served as a contributing editor to Science Translational Medicine, is appointed as a domain expert for the Singapore Precision Medicine initiative, holds an active MOU with Agilent Corporation and currently sits on the Board of Directors, Asian Scientist Publishing.

Honors & Awards


2017: BCLS and AED certification
2015: BCLS and AED certification
2013: Promoted from Associate Consultant to Full Consultant, Department of Cardiology
2012: Certified SMC Cardiology
2012: Certified SMC Internal Medicine
2009: Board Certified, Cardiology, ABIM
2008: Cardiology fellowship, Brigham and Women’s Hospital, Harvard Medical School
2007: Board Certified, Internal Medicine, ABIM
2005: Internal Medicine Residency, Univ. Calif. San Diego
2003: Ph.D. (Neurobiology), University of Chicago
2003: M.D., University of Chicago, Pritzker School of Medicine
1994: B.A., University of Chicago

Awards & Grants

2016 SMART Innovation Award, SMART, Singapore (250,000 SGD)
2014 Saphire (2,100,000 SGD)
2014 SMART Innovation Award, SMART, Singapore (250,000 SGD)
2013 SMART Innovation Award, SMART, Singapore (250,000 SGD)
2012 Clinician Scientist Award, NMRC, Singapore (675,000 SGD)
2009 Burroughs Wellcome CAMS Award, USA (250,000 USD)
2008 Leadership Council in Cardiology Award, USA (50,000 USD)
2003 Harold Lamport Award for the Top Dissertation Submitted to the Biological Sciences
University of Chicago, USA
2002 Award for Difficult Structure Determination of the Year, Gordon Conference, USA
1995 Summer Research Award, University of Chicago, USA
1994 Graduation with Honors, University of Chicago, USA

Years of Experience

  • Cardiology
  • Biochemistry
  • Therapeutic Discovery